Research in the Bradke lab focuses on how nerve cells grow during development and how these processes can be reactivated to induce nerve regeneration in the injured spinal cord.

This laboratory has a special interest in the skeleton of the cell, called the cytoskeleton.

Bradke and his coworkers showed that manipulation of the cytoskeleton with low doses of anticancer drugs leads to regrowth of nerves and reduction of scarring.

His lab also developed a novel imaging technique that enables visualization of nerves at microscopic resolution within whole tissue.