Award: Susanne Wegmann, PhD, is one of the “100 Minds of Science” in Berlin

Who are the leading figures in science in and around Berlin? The team of science editors of the Berlin-based newspaper “Tagesspiegel” has selected the “100 wichtigsten Köpfe der Berliner Wissenschaft 2024” (100 most important minds of 2024). This directory comprises outstanding scientists who are notable for their research achievements or excellent teaching. Others show a particular social commitment and shape social debates. 

Among the selected researchers is a scientist from DZNE: Susanne Wegmann, PhD, group leader at DZNE's site Berlin. The biophysicist is one of the most renowned experts in the field of tau research and associated dementias: she wants to decode the protein tau – this protein plays a key role in the development of certain degenerative brain diseases such as Alzheimer's and frontotemporal dementia. The protein exists in a healthy, soluble form in every neuron of the brain. In a healthy brain, it helps to stabilize the scaffolding of neurons. However, if tau accumulates and aggregates within neurons, it causes destruction of synapses and cell death. The consequence is a progressive dysfunction of cognitive, motor and psychological abilities.

Wegmann and her Berlin research group are investigating why deposits of tau form in neurons – and how exactly the protein influences elementary cellular processes. Answering these questions could open up new therapeutic possibilities in the future. Susanne Wegmann was honored by the “Tagesspiegel” for her research.

Further information:

You can read a portrait of Susanne Wegmann and her research here.

In episode 40 “Alzheimer's and the Enigmatic Tau Protein” of our science podcast “Hirn & Heinrich”, Susanne Wegmann describes what an anti-tau therapy for Alzheimer's could look like. She also talks to Sabine Heinrich about her commitment to young scientists in Central and South America.