Study outpatient clinic
We provide a central platform for the professional conduct of observational and interventional therapeutic clinical studies at the DZNE Munich.
Our work focuses on the investigation of etiologically defined neurodegenerative diseases:
- Autosomal dominant Alzheimer's disease (Amyloid-beta pathology)
- Early onset Alzheimer's disease (genetic amyloid beta risk constellations)
- Frontotemporal dementia (FTD; genetic risk constellations in TARDBP, GRN, C9orf72, FUS, MAPT)
- Progressive Supranuclear Paresis, Corticobasal Degeneration (PSP / CBD; 4R-Tau Pathology)
- Parkinson's disease, including with GBA mutations (neuronal synuclein pathology)
- Multisystem Atrophy (MSA; glial synuclein pathology)
- Vascular-related neurodegeneration (monogenic vascular diseases; vascular cognitive impairment, vascular Parkinsonism)
Tasks
- Key tasks
- Ermöglichung interventioneller Therapie-Studien
- Biobanking nach DZNE Biobank-Regularien (DNA, Serum, Fibroblasten, …)
- Entwicklung weiterer DZNE Projekte entsprechend den Regularien der klinischen Forschung am DZNE
- Tasks in cooperation
- Molecular diagnostics (genetics, biomarkers[e. g. progranulin], PET[Amyloid, Tau])
- Imaging diagnostics (MRI, PET[FDG], SPECT[FP-CIT, IBZM])
Contact
Francesca Talpo (Office)
francesca.talpo(at)dzne.de
Adress
Klinische DZNE Studieneinheit
Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)
Feodor-Lynen Str. 17
D-81377 München