Prof. Dr. Frank Bradke

Group Leader

Venusberg-Campus 1/99
53127 Bonn

frank.bradke(at)dzne.de +49 228 43302-688

Featured Publications

Vinopal, S. (First author) ; Dupraz, S. ; Alfadil, E. ; Pietralla, T. ; Bendre, S. ; Stiess, M. ; Falk, S. ; Camargo Ortega, G. ; Maghelli, N. ; Tolić, I. M. ; Smejkal, J. ; Götz, M. ; Bradke, F. (Last author)
Centrosomal microtubule nucleation regulates radial migration of projection neurons independently of polarization in the developing brain.
Neuron 111(8), 1241 - 1263.e16 (2023) [10.1016/j.neuron.2023.01.020]2023 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Griffin, J. (First author) ; Hingorani Jai Prakash, S. ; Bockemühl, T. ; Benner, J. M. ; Schaffran, B. ; Moreno-Manzano, V. ; Büschges, A. ; Bradke, F. (Last author)
Rehabilitation enhances epothilone-induced locomotor recovery after spinal cord injury.
Brain communications 5(1), fcad005 (2023) [10.1093/braincomms/fcad005]2023 OpenAccess Files Fulltext Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Schelski, M. (First author) ; Bradke, F. (Last author)
Microtubule retrograde flow retains neuronal polarization in a fluctuating state.
Science advances 8(44), eabo2336 (2022) [10.1126/sciadv.abo2336]2022 OpenAccess Files Fulltext Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Hilton, B. J. (First author) ; Husch, A. ; Schaffran, B. ; Lin, T.-C. ; Burnside, E. R. ; Dupraz, S. ; Schelski, M. ; Kim, J. ; Müller, J. A. ; Schoch, S. ; Imig, C. ; Brose, N. ; Bradke, F. (Last author)
An active vesicle priming machinery suppresses axon regeneration upon adult CNS injury.
Neuron 110(1), 51 - 69.e7 (2022) [10.1016/j.neuron.2021.10.007]2022 OpenAccess Files Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Stern, S. (First author) ; Hilton, B. J. ; Burnside, E. ; Dupraz, S. ; Handley, E. ; Gonyer, J. ; Brakebusch, C. ; Bradke, F. (Last author)
RhoA drives actin compaction to restrict axon regeneration and astrocyte reactivity after CNS injury.
Neuron 109(21), 3436 - 3455.e9 (2021) [10.1016/j.neuron.2021.08.014]2021 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Da Silva Santos, T. (First author) ; Schaffran, B. ; Broguière, N. ; Meyn, L. ; Zenobi-Wong, M. ; Bradke, F. (Last author)
Axon Growth of CNS Neurons in Three Dimensions Is Amoeboid and Independent of Adhesions
Cell reports 32(3), 107907 (2020) [10.1016/j.celrep.2020.107907]2020 OpenAccess Files Fulltext BibTeX | EndNote: XML, Text | RIS

Dupraz, S. ; Hilton, B. J. ; Husch, A. ; Da Silva Santos, T. ; Coles, C. H. ; Stern, S. ; Brakebusch, C. ; Bradke, F. (First author)
RhoA Controls Axon Extension Independent of Specification in the Developing Brain.
Current biology 29(22), 3874-3886.e9 (2019) [10.1016/j.cub.2019.09.040]2019 OpenAccess Files BibTeX | EndNote: XML, Text | RIS

Tedeschi, A. ; Dupraz, S. ; Curcio, M. ; Laskowski, C. J. ; Schaffran, B. ; Flynn, K. C. ; Da Silva Santos, T. ; Stern, S. ; Hilton, B. J. ; Larson, M. J. E. ; Gurniak, C. B. ; Witke, W. ; Bradke, F. (First author)
ADF/Cofilin-Mediated Actin Turnover Promotes Axon Regeneration in the Adult CNS.
Neuron 103(6), 1073-1085.e6 (2019) [10.1016/j.neuron.2019.07.007]2019 pmc Files Fulltext Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Hilton, B. J. (First author) ; Blanquie, O. ; Tedeschi, A. ; Bradke, F. (Last author)
High-resolution 3D imaging and analysis of axon regeneration in unsectioned spinal cord with or without tissue clearing.
Nature protocols 14(4), 1235-1260 (2019) [10.1038/s41596-019-0140-z]2019 Fulltext BibTeX | EndNote: XML, Text | RIS

Ruschel, J. (First author) ; Bradke, F.
Systemic administration of epothilone D improves functional recovery of walking after rat spinal cord contusion injury.
Experimental neurology 306, 243-249 (2018) [10.1016/j.expneurol.2017.12.001]2018 Fulltext BibTeX | EndNote: XML, Text | RIS

Tedeschi, A. (First author) ; Dupraz, S. ; Laskowski, C. J. ; Xue, J. ; Ulas, T. ; Beyer, M. ; Schultze, J. L. ; Bradke, F. (Last author)
The Calcium Channel Subunit Alpha2delta2 Suppresses Axon Regeneration in the Adult CNS.
Neuron 92(2), 419-434 (2016) [10.1016/j.neuron.2016.09.026]2016 Files Fulltext BibTeX | EndNote: XML, Text | RIS

Flynn, K. C. (First author) ; Hellal, F. ; Neukirchen, D. ; Jacob, S. ; Tahirovic, S. ; Dupraz, S. ; Stern, S. ; Garvalov, B. K. ; Gurniak, C. ; Shaw, A. E. ; Meyn, L. ; Wedlich-Söldner, R. ; Bamburg, J. R. ; Small, J. V. ; Witke, W. ; Bradke, F. (Last author)
ADF/cofilin-mediated actin retrograde flow directs neurite formation in the developing brain.
Neuron 76(6), 1091-1107 (2012) [10.1016/j.neuron.2012.09.038]2012 Files Fulltext BibTeX | EndNote: XML, Text | RIS

Ertürk, A. ; Mauch, C. P. ; Hellal, F. ; Förstner, F. ; Keck, T. ; Becker, K. ; Jährling, N. ; Steffens, H. ; Richter, M. ; Hübener, M. ; Kramer, E. ; Kirchhoff, F. ; Dodt, H. U. ; Bradke, F. (Last author)
Three-dimensional imaging of the unsectioned adult spinal cord to assess axon regeneration and glial responses after injury.
Nature medicine 18(1), 166-171 (2011) [10.1038/nm.2600]2011 Files Fulltext BibTeX | EndNote: XML, Text | RIS

Publications

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