Prof. Dr. Stefan Lichtenthaler

Group Leader

Feodor-Lynen-Str. 17
81377 München

stefan.lichtenthaler(at)dzne.de +49 89 4400-46425

Featured Publications

Schmidt, A. (First author) ; Hrupka, B. ; van Bebber, F. ; Sunil Kumar, S. ; Feng, X. ; Tschirner, S. K. ; Aßfalg, M. ; Müller, S. A. ; Hilger, L. S. ; Hofmann, L. I. ; Pigoni, M. ; Jocher, G. ; Voytyuk, I. ; Self, E. L. ; Ito, M. ; Hyakkoku, K. ; Yoshimura, A. ; Horiguchi, N. ; Feederle, R. ; De Strooper, B. ; Schulte-Merker, S. ; Lammert, E. ; Moechars, D. ; Schmid, B. ; Lichtenthaler, S. F. (Last author)
The Alzheimer's disease-linked protease BACE2 cleaves VEGFR3 and modulates its signaling.
The journal of clinical investigation 134(16), e170550 (2024) [10.1172/JCI170550]2024 OpenAccess Files Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Müller, S. A. (First author) ; Shmueli, M. D. ; Feng, X. ; Tüshaus, J. ; Schumacher, N. ; Clark, R. ; Smith, B. E. ; Chi, A. ; Rose-John, S. ; Kennedy, M. E. ; Lichtenthaler, S. F. (Last author)
The Alzheimer’s disease-linked protease BACE1 modulates neuronal IL-6 signaling through shedding of the receptor gp130
Molecular neurodegeneration 18(1), 13 (2023) [10.1186/s13024-023-00596-6]2023 OpenAccess Files Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Güner, G. (First author) ; Assfalg, M. ; Zhao, K. ; Dreyer, T. ; Lahiri, S. ; Lo, Y. ; Slivinschi, B. ; Imhof, A. ; Jocher, G. ; Strohm, L. ; Behrends, C. ; Langosch, D. ; Bronger, H. ; Nimsky, C. ; Bartsch, J. W. ; Riddell, S. R. ; Steiner, H. ; Lichtenthaler, S. (Last author)
Proteolytically generated soluble Tweak Receptor Fn14 is a blood biomarker for γ-secretase activity.
EMBO molecular medicine 14(10), e16084 (2022) [10.15252/emmm.202216084]2022 OpenAccess Files Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

McDade, E. ; Voytyuk, I. ; Aisen, P. ; Bateman, R. J. ; Carrillo, M. C. ; De Strooper, B. ; Haass, C. ; Reiman, E. M. ; Sperling, R. ; Tariot, P. N. ; Yan, R. ; Masters, C. L. ; Vassar, R. ; Lichtenthaler, S. F. (Last author)
The case for low-level BACE1 inhibition for the prevention of Alzheimer disease.
Nature reviews / Neurology 17(11), 703 - 714 (2021) [10.1038/s41582-021-00545-1]2021 Files BibTeX | EndNote: XML, Text | RIS

Tüshaus, J. (First author) ; Müller, S. A. ; Kataka, E. S. ; Zaucha, J. ; Sebastian Monasor, L. ; Su, M. ; Güner, G. ; Jocher, G. ; Tahirovic, S. ; Frishman, D. ; Simons, M. ; Lichtenthaler, S. (Last author)
An optimized quantitative proteomics method establishes the cell type-resolved mouse brain secretome.
The EMBO journal 39(20), e105693 (2020) [10.15252/embj.2020105693]2020 OpenAccess Files Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Lichtenthaler, S. F. (First author) ; Güner, G. (Last author)
Pathology-linked protease caught in action.
Science / Science now 363(6428), 690-691 (2019) [10.1126/science.aaw5547]2019 Files BibTeX | EndNote: XML, Text | RIS

Lichtenthaler, S. (First author) ; Lemberg, M. K. ; Fluhrer, R.
Proteolytic ectodomain shedding of membrane proteins in mammals-hardware, concepts, and recent developments.
The EMBO journal 37(15), e99456 (2018) [10.15252/embj.201899456]2018 pmc Files Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Publications

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