Clinical studies at the Berlin site
If you would like to support our research by participating, you can find here an overview of all studies for which we are currently looking for subjects at the Berlin site.
You can refine your search using the filters for the target group or a specific diagnosis.
ABCD
The aim of this study is to investigate the influence of rituximab (Rixathon®) on the progression of disease in patients with amyotrophic lateral sclerosis (ALS) compared to a placebo. The study is funded by the German Federal Ministry of Education and Research (BMBF).
DANCER (Establishment of a Recruitment Pool of Potential Study Participants, of Realtives and a Control Group for DZNE Studies)
One focus of these studies is the identification of early, specific changes, for example in the blood, so that the diagnosis of a neurodegenerative disease such as dementia or Parkinson's can be made at a very early stage. This enables a better understanding of the diseases and supports the development of new forms of therapy.
DANCER-PSP (Recruitment of Realtives and a Control Group for the DESCRIBE-PSP Study)
Comparative studies with relatives of patients with PSP and interested individuals without a diagnosis of neurodegenerative disease are needed to assess study outcomes of patients with progressive supranuclear palsy (PSP).
DESCRIBE (DZNE - Clinical Register Study of neurodegenerative Disorders)
The aim of the DESCRIBE study is to use the examination results obtained in the course of normal patient care together with findings from diagnostics on biomaterials, including genetic analysis, for scientific purposes.
DESCRIBE-FTD (DZNE - Clinical Registry Study on Frontotemporal Dementia (FTD))
The aim of the DESCRIBE-FTD study is to describe in detail the course of FTD in its various clinical manifestations. The aim is to gain a better understanding of the underlying pathology and to identify parameters that enable diagnosis and prediction of the course of the disease.
DESCRIBE-PSP (DZNE - Clinical Registry Study on Progressive Supranuclear Paresis (PSP))
The aim of the DESCRIBE-PSP study is to document the early and atypical course of PSP in order to enable improved diagnostic criteria and therapy studies in the early course of the disease.
DZNE-CAA (DZNE Cerebral Amyloid Angiopathy Study)
Cerebral amyloid angiopathy (CAA) is a disease of the vessels in the brain in which proteins, known as amyloid, are deposited in the walls of the vessels. There are initial indications of possible mechanisms and biomarkers that influence the course of the disease, but there are still many unanswered questions.
ENABLE (Patient- and care-related benefits of amyloid PET imaging)
The aim of the ENABLE trial is to test whether amyloid PET screening has the potential to improve the care of dementia patients in the German health care system and thus contribute to the preservation or slowed loss of everyday functions.
PROMINENT (Improving the management of Alzheimer’s disease)
PROMINENT is a collaborative pan-European public-private partnership funded through the Innovative Health Initiative (IHI). It will create a digital platform for precision medicine to improve the diagnosis and treatment of neurodegenerative disease and co-morbidities to assist clinicians with individualised decision support in the evaluation of patients with suspected cognitive impairment.
PROSA (A Low-burden High-frequency PROgnostic Digital Speech Biomarker to Improve Future Confirmatory ALS and FTD Trials)
Development and validation of a novel speech biomarker for the ALS-FTD disease spectrum based on speech measurements that can be collected repeatedly and remotely by telephone to assess three key symptom groups: Cognition (language, executive functions and memory), motor function and respiratory function.
Prospect-AD (Population-based screening over speech for clinical trials in Alzheimer’s Disease)
Subjective memory impairment (SCD) or mild cognitive impairment (MCI) may be associated with an increased risk of dementia later in life. Early preventive measures can potentially reduce the risk of dementia. This requires early detection of early signs of cognitive impairment.
REMINDer (Online study to evaluate the feasibility and effectiveness of a multimodal online exercise program for elderly adults)
The DZNE Dresden is investigating the feasibility and effectiveness of a six-week multimodal online program with music, movement and mindfulness exercises for people aged 60 - 80 years.
REMINDer (Preparedness of German specialists and memory clinics to deliver early and accurate diagnosis for AD disease‐modifying treatment)
The DZNE is conducting a nationwide online survey among memory outpatient clinics and neurological and psychiatric medical practices to assess their ability to make an early and accurate diagnosis for disease-modifying treatment of Alzheimer's disease.