Areas of investigation/research focus
Our group focuses on understanding how the immune system responds to changes in the brain's microenvironment during healthy aging and neurodegeneration. We also…
BACE1: A crucial enzyme in the formation of amyloid
When the enzyme BACE1 was discovered at the turn of the millennium, hope for an effective Alzheimer's drug flared up for a moment: The enzyme is…
ADAM10: A protective shield against the harmful amyloid
The ADAM10 enzyme can be imagined as a pair of scissors: In the nerve cells of the brain, it attaches itself to a specific protein, which it…
Research focus
Research focus is to develop, refine and apply data-driven approaches to better understand the disease course of spinocerebellar ataxias. The work is based on longitudinal studies of…
The most important facts in brief:
Vascular dementia develops because of inadequate blood flow to the brain The first symptoms of vascular dementia include general slowing, difficulty…
More than just tremor
Parkinson's disease is the second most common neurodegenerative disease – right after Alzheimer's disease. According to estimates, there are at least 200,000 people affected in…
Sensory illusions and mental and physical impairments
Lewy body dementia usually occurs after the age of 65. To date, it is not really clear whether Lewy body dementia is a disease in its own…
Progressive loss of cognitive abilities
Dementia is not just a matter of age. Children and adolescents can also be affected by progressive neurodegenerative diseases. More than 250 different…
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