More than just the movement disorder "St. Vitus' dance"
Huntington's chorea, also called “Huntington’s disease” or "Morbus Huntington", is a dominantly inherited disorder of the brain. It was named…
Altered personality and conspicuous social behavior
Frontotemporal dementia (FTD) is a rare form of rapidly progressive dementia. It is estimated that, together with Alzheimer's, it accounts for the…
When movements become disordered
The term "ataxia" is derived from the Greek word "a-taxia" meaning "a lack of order". Ataxia is the name for a number of rare disorders of the brain and spinal cord…
Slipping into forgetting
According to projections, there are currently around 1.8 million people living with dementia in Germany – and numbers are rising. The majority of them are affected by…
When movement dies
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that affects a very specific group of neurons: the neurons for voluntary motor function, also known as motor…
TREM2: A booster against Alzheimer's?
A protein may hold potential starting points for a therapy against Alzheimer's disease. The current finding is that the higher the TREM2 level, the better the…
Tau: When a protein paralyzes the flow of information
In Alzheimer's patients, the protein tau gets out of control. Deposits form in the nerve cells, blocking the exchange of information and…
The number one Alzheimer's risk factor
The protein ApoE4 is considered the most important genetic risk factor for Alzheimer's disease.
One of the central questions in Alzheimer's research is…
Amyloid: the trigger of a lethal cascade leading to nerve cell death
In Alzheimer's patients, clumps of amyloid form in the brain long before the first symptoms appear. They play a central role in…
Clinical Research Platform
The multi-site studies of the DZNE are supported and coordinated by the Clinical Research Platform (CRP) at the Centre for Clinical Research in Bonn. Within the clinical…
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